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產(chǎn)品英文名稱：PE Mouse Anti-Human CD10
產(chǎn)品中文名稱：PE鼠抗人CD10
BD PE鼠抗人CD10 PE Mouse Anti-Human CD10產(chǎn)品英文描述：
Catalog Number 347653
Name Cytokeratin
Size 100 Tests
Regulatory Status RUO (GMP)
List Price Inquire
Related Molecules KRT7
Clone CAM 5.2
Format FITC
Isotype IgG2a, κ
W.S. No none
W.B. Positive Control none
Molecular Weight none
Reactivity QC Testing : Human
Applications Routinely Tested:Intracellular staining (flow cytometry)
Reacts with neutral endopeptidase, a 100 kDa type II transmembrane glycoprotein, otherwise known as the common acute lymphoblastic
leukemia antigen (CALLA). CD10 is expressed on a wide variety of normal and neoplastic cell types. Normal cells expressing CD10 include
granulocytes, a subset of B-cell progenitors, germinal center cells and fibroblasts.
Clone - Description
Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, Mr 48 and 52 kDa, respectively.Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) may not react with some squamous cell carcinomas.
BD PE鼠抗人CD10 PE Mouse Anti-Human CD10單克隆抗體多樣性的遺傳學基礎：
L鏈H鏈相互隨機配對 如表2-6所示，小鼠H鏈和κ鏈隨機配對后推算其多樣性可達4.8×107，如果再加上H鏈與λ鏈的隨機配對其多樣性應更多了。
產(chǎn)品規(guī)格：0.1ml/0.2ml
儲 存： -20℃環(huán)境下存放. 封閉保存,否則會降低產(chǎn)品含量.
產(chǎn)品用途：本產(chǎn)品僅供科研使用，不做其他用途
產(chǎn)品價格：電詢咨詢
基因重排：
1）抗體的L鏈是由C、V、J三個基因簇編碼的，H鏈由C、V、D、J四個基因簇編碼的。
2）V是編碼可變區(qū)，有300個種類;D編碼高變區(qū),有15 ～ 20個種類;J編碼連接V、C的結合區(qū)，有4～5個種類;C編碼恒定區(qū)，僅有一種。
3）這些外顯子通過多種多樣的重排，所合成出的肽鏈，還要再進一步進行L和H鏈組合，這樣zui后生成的抗體種類就非常多了。
4）抗體基因重排是發(fā)生在淋巴細胞分化的時候
華雅再生醫(yī)學工程技術有限公司是一家為干細胞研究員提供干細胞無血清培養(yǎng)基，支原體檢測試劑盒，心肌細胞株，人間充質(zhì)干細胞株，凍存管凍存盒，臍帶間充質(zhì)干細胞凍存袋，細胞實驗耗材等進口品牌高質(zhì)量產(chǎn)品。專注干細胞研究，關注干細胞治療產(chǎn)品，購買干細胞產(chǎn)品請到華雅再生醫(yī)學工程公司。
