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StemRD LDN-193189 小分子工具
StemRD LDN-193189 小分子工具A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3). Only weakly inhibits ALK-4,-5, and -7. 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1
產(chǎn)品英文名稱:LDN-193189, ALK-2, -3 Inhibitor
產(chǎn)品中文名稱:LDN-193189 ALK-2,-3 抑制劑
LDN-193189 產(chǎn)品英文簡(jiǎn)述:
A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3). Only weakly inhibits ALK-4,-5, and -7.
4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Ref: Cuny, G.D., et al. Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008.
• Purity: Greater than 98% as determined by LC/MS analysis.
• Biological Activity: Not Determined
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